Cell Reproduction Crossword Puzzle – Vocab Review
An 18-clue crossword reviews cell-division vocabulary, from interphase and cytokinesis to mitosis phases and cancer-related terms, with a separate completed answer key.

- Grades
- Grades 9–12
- File type
- Multiple File Types
- Subject
- Science, Life Sciences, Human Body
- Topic
- Anatomy, Physiology
- Resource types
- Crosswords Puzzles, Worksheets, Worksheets & Printables
From the author
About this resource
This crossword puzzle is great for vocabulary building and can be used during a Cell unit as a post test activity, homework assignment, etc. This product includes the Cell Reproduction crossword puzzle and the answer key.
In the classroom
Teaching tips & learning objectives
Learning objectives
- Define key vocabulary from the cell cycle and mitosis, including interphase, cytokinesis, chromosome, and chromatid
- Identify structures and events involved in mitosis, such as the centromere, centriole, and metaphase
- Connect abnormal cell division to cancer-related vocabulary, including carcinogen and uncontrolled cell growth
Teaching tips
- Assign after directly teaching the mitosis phases, since the puzzle offers no word bank and relies on recall rather than recognition.
- Use the answer key to let students self-check in pairs rather than grading every puzzle individually.
- If copying clue text out of the PDF for a digital or accessible version, retype it manually — the file uses a custom crossword font that does not extract cleanly as plain text.
Skills covered
- Cell biology vocabulary
- Mitosis
- Science vocabulary review
Good to know
Questions teachers ask about this resource
Is a word bank provided to help students who get stuck?
No — the puzzle lists only numbered across and down clues with no word bank; students must recall the vocabulary term itself.
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Resource details
Concepts & topics
Core concepts
- Cell cycle
- Mitosis phases
- Chromosomes and chromatids